Application Notes
• Co-developed with Nikon representatives while working as a Senior Scientific Content Specialist at Ronawk
• Introduces a broader scientific audience to the Ronawk's Bio-Block
◦ Focused on novel characteristics of the Bio-Block cell culture system
• Provides technical information about Nikon's confocal microscope and associated hardware that allow for high-quality confocal imaging
◦ Emphasized on the new NSPARC array detector
Abstract
Ronawk’s Bio-Blocks™ enable cell culture in a 3D, tissue-mimetic environment, which allows cells to form intricate 3D structures and tissue-like aggregates. The more true-to-life microenvironment of the Bio-Blocks drives cells to adopt physiologically-relevant behaviors that occur in vivo, where they explore, signal, replicate, and build complex networks. However, capturing both 3D multicellular structure and the underlying subcellular detail poses a challenge for scientists studying cellular activity within tissues and tissue-mimetic cultures. Towards this goal, the Nikon AX R confocal microscope equipped with the NSPARC array detector enables fast and efficient acquisition of high-resolution, optically-sectioned images throughout the sample volume. The combination of cutting-edge cell culture and imaging technologies reveals the microscopic world of tissue-mimetic cells and tissue cultures with striking subcellular detail. The imaging capabilities of the Nikon AX R with NSPARC showcase the biological potential of the Ronawk Bio-Block platform and highlight opportunities for future research.
Contract Service Reports
• Due to confidentiality and non-disclosure agreements I unable to share direct examples for this class of work
• I have used my dissertation as source material for an example, since it bears several similarities to many aspects of contract service report drafting
◦ Examples are provided below with more detail.
Technical Document Drafting in Microsoft Word
• Document contents drafted in compliance with style guides or other regulation as required by policy
• Signature page(s) for document review and approval using wet ink and/or digital signatures
• Table of Contents (ToC) with functional navigation links to document (sub)sections, figures, tables, and appendices
• Appropriate use of citations, footnotes, internal cross-references, among other technical elements
• Processed data are incorporated from a range of source file types across an array of assay types
• Established process for drafting, revising, and submitting final version of the document
• Document can be exported to PDF as part of the deliverables . PDF is compliant with requirements for submissions and acceptance.
Customer Protocols
• Collaboratively drafted, edited, and illustrated protocols while working as a Senior Scientific Content Specialist at Ronawk
◦ Each protocol includes custom, protocol-specific illustration that are drawn to scale for additional clarity